Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Col2a1  collagen, type II, alpha 1   (Synonyms: Col2, Col2a, Col2a-1, Del1, Lpk, M100413, M100856, Rgsc413, Rgsc856)
Results	Reference
1*	J:132300 Amin S, Matalova E, Simpson C, Yoshida H, Tucker AS, Incudomalleal joint formation: the roles of apoptosis, migration and downregulation. BMC Dev Biol. 2007;7:134
1	J:222437 Aoto K, Sandell LL, Butler Tjaden NE, Yuen KC, Watt KE, Black BL, Durnin M, Trainor PA, Mef2c-F10N enhancer driven beta-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells. Dev Biol. 2015 Jun 1;402(1):3-16
1	J:51376 Aszodi A, Chan D, Hunziker E, Bateman JF, Fassler R, Collagen II is essential for the removal of the notochord and the formation of intervertebral discs. J Cell Biol. 1998 Nov 30;143(5):1399-412
1	J:75823 Aubin J, Lemieux M, Moreau J, Lapointe J, Jeannotte L, Cooperation of Hoxa5 and Pax1 Genes during Formation of the Pectoral Girdle. Dev Biol. 2002 Apr 1;244(1):96-113
1	J:217672 Blazek JD, Malik AM, Tischbein M, Arbones ML, Moore CS, Roper RJ, Abnormal mineralization of the Ts65Dn Down syndrome mouse appendicular skeleton begins during embryonic development in a Dyrk1a-independent manner. Mech Dev. 2015 May;136:133-42
1	J:198653 Blitz E, Sharir A, Akiyama H, Zelzer E, Tendon-bone attachment unit is formed modularly by a distinct pool of Scx- and Sox9-positive progenitors. Development. 2013 Jul;140(13):2680-90
1	J:214083 Boucherat O, Nadeau V, Berube-Simard FA, Charron J, Jeannotte L, Crucial requirement of ERK/MAPK signaling in respiratory tract development. Development. 2014 Aug;141(16):3197-211
1	J:213873 Chen Z, Huang J, Liu Y, Dattilo LK, Huh SH, Ornitz D, Beebe DC, FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands. Development. 2014 Jul;141(13):2691-701
1	J:309485 Colasanto MP, Eyal S, Mohassel P, Bamshad M, Bonnemann CG, Zelzer E, Moon AM, Kardon G, Development of a subset of forelimb muscles and their attachment sites requires the ulnar-mammary syndrome gene Tbx3. Dis Model Mech. 2016 Nov 1;9(11):1257-1269
1	J:221660 Eyal S, Blitz E, Shwartz Y, Akiyama H, Schweitzer R, Zelzer E, On the development of the patella. Development. 2015 May 15;142(10):1831-9
1	J:272612 Eyal S, Rubin S, Krief S, Levin L, Zelzer E, Common cellular origin and diverging developmental programs for different sesamoid bones. Development. 2019 Feb 28;146(4):dev167452
1	J:246663 Garg A, Bansal M, Gotoh N, Feng GS, Zhong J, Wang F, Kariminejad A, Brooks S, Zhang X, Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis. PLoS Genet. 2017 Oct;13(10):e1007047
1	J:266214 Garg A, Hannan A, Wang Q, Collins T, Teng S, Bansal M, Zhong J, Xu K, Zhang X, FGF-induced Pea3 transcription factors program the genetic landscape for cell fate determination. PLoS Genet. 2018 Sep;14(9):e1007660
1	J:223502 Hata K, Takashima R, Amano K, Ono K, Nakanishi M, Yoshida M, Wakabayashi M, Matsuda A, Maeda Y, Suzuki Y, Sugano S, Whitson RH, Nishimura R, Yoneda T, Arid5b facilitates chondrogenesis by recruiting the histone demethylase Phf2 to Sox9-regulated genes. Nat Commun. 2013;4:2850
1	J:109399 Ichikawa Y, Sumi M, Ohwatari N, Komori T, Sumi T, Shibata H, Furuichi T, Yamaguchi A, Nakamura T, Evaluation of 9.4-T MR microimaging in assessing normal and defective fetal bone development: comparison of MR imaging and histological findings. Bone. 2004 Apr;34(4):619-28
1*	J:194983 Ideno H, Shimada A, Imaizumi K, Kimura H, Abe M, Nakashima K, Nifuji A, Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development. Gene Expr Patterns. 2013 Mar-Apr;13(3-4):84-90
1	J:81856 Ihanamaki T, Saamanen AM, Suominen J, Pelliniemi LJ, Harley V, Vuorio E, Salminen H, Expression of Sox9 and type IIA procollagen during ocular development and aging in transgenic Del1 mice with a mutation in the type II collagen gene. Eur J Ophthalmol. 2002 Nov-Dec;12(6):450-8
1*	J:236167 Li J, Manickam G, Ray S, Oh CD, Yasuda H, Moffatt P, Murshed M, Smpd3 Expression in both Chondrocytes and Osteoblasts Is Required for Normal Endochondral Bone Development. Mol Cell Biol. 2016 Sep 1;36(17):2282-99
1*	J:52896 Masuda H, Hosokawa N, Nagata K, Expression and localization of collagen-binding stress protein Hsp47 in mouse embryo development: comparison with types I and II collagen. Cell Stress Chaperones. 1998 Dec;3(4):256-64
1	J:255459 Nara M, Kitamura K, Yamamoto M, Nagakura R, Mitomo K, Matsunaga S, Abe S, Developmental mechanism of muscle-tendon-bone complex in the fetal soft palate. Arch Oral Biol. 2017 Oct;82:71-78
1*	J:321553 Neupane S, Berardinelli SJ, Cameron DC, Grady RC, Komatsu DE, Percival CJ, Takeuchi M, Ito A, Liu TW, Nairn AV, Moremen KW, Haltiwanger RS, Holdener BC, O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development. Matrix Biol. 2022 Feb 12;
1	J:106936 Pimanda JE, Silberstein L, Dominici M, Dekel B, Bowen M, Oldham S, Kallianpur A, Brandt SJ, Tannahill D, Gottgens B, Green AR, Transcriptional link between blood and bone: the stem cell leukemia gene and its +19 stem cell enhancer are active in bone cells. Mol Cell Biol. 2006 Apr;26(7):2615-25
1	J:147280 Pryce BA, Watson SS, Murchison ND, Staverosky JA, Dunker N, Schweitzer R, Recruitment and maintenance of tendon progenitors by TGF{beta} signaling are essential for tendon formation. Development. 2009 Apr;136(8):1351-61
1	J:147287 Retting KN, Song B, Yoon BS, Lyons KM, BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation. Development. 2009 Apr;136(7):1093-104
1	J:202984 Rockich BE, Hrycaj SM, Shih HP, Nagy MS, Ferguson MA, Kopp JL, Sander M, Wellik DM, Spence JR, Sox9 plays multiple roles in the lung epithelium during branching morphogenesis. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4456-64
1	J:167739 Sala FG, Del Moral PM, Tiozzo C, Alam DA, Warburton D, Grikscheit T, Veltmaat JM, Bellusci S, FGF10 controls the patterning of the tracheal cartilage rings via Shh. Development. 2011 Jan;138(2):273-82
1	J:45403 Shibata S, Fukada K, Suzuki S, Yamashita Y, Immunohistochemistry of collagen types II and X, and enzyme-histochemistry of alkaline phosphatase in the developing condylar cartilage of the fetal mouse mandible. J Anat. 1997 Nov;191(Pt 4):561-70
1	J:234264 Shwartz Y, Viukov S, Krief S, Zelzer E, Joint Development Involves a Continuous Influx of Gdf5-Positive Cells. Cell Rep. 2016 Jun 21;15(12):2577-87
1	J:137353 Sohaskey ML, Yu J, Diaz MA, Plaas AH, Harland RM, JAWS coordinates chondrogenesis and synovial joint positioning. Development. 2008 Jul;135(13):2215-20
1	J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51
1*	J:32201 Wood A, Ashhurst DE, Corbett A, Thorogood P, The transient expression of type II collagen at tissue interfaces during mammalian craniofacial development. Development. 1991 Apr;111(4):955-68
1	J:97410 Yoon BS, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo. Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):5062-7
1	J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78